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近日,国家卫健委肿瘤蛋白质组学重点实验室在国际权威杂志Signal Transduction and Targeted Therapy(信号转导与靶向治疗,IF=38.104)发表了题为“Targeting p53 pathways: mechanisms, structures, and advances in therapy”(靶向p53通路:机制、结构和治疗的进展)的文章。第一作者为博士研究...
肿瘤微环境(tumor microenvironment,TME)在肿瘤恶性和治疗抵抗中发挥着重要作用。近年来,根据TME特点挖掘潜在靶点并开发安全有效的免疫疗法逐渐成为乳腺癌治疗的研究热点。2018年7月27日,复旦大学生物医学研究院/附属肿瘤医院柳素玲团队在PLOS Biology杂志在线发表了题为CCL20 triggered by chemotherapy hinders the ther...
近日,中南大学基础医学院 肿瘤研究所研究员陶永光团队与病理学系教授肖德胜团队在国际期刊Signal Transduction and Targeted Therapy(STTT, IF=38.104)发表了题为“GPR162 activates STING dependent DNA damage pathway as a novel tumor suppressor and radiation ...
近日,中南大学湘雅医院病理科陶永光研究员与肖德胜教授团队在国际期刊Signal Transduction and Targeted Therapy(信号转导与靶向治疗,STTT,IF=38.104)发表了题为“GPR162 activates STING dependent DNA damage pathway as a novel tumor suppressor and radiation s...
近日,中南大学基础医学院病理学系教授肖德胜团队与肿瘤研究所研究员陶永光团队在国际期刊Signal Transduction and Targeted Therapy发表了题为“The cross-talk between methylation and phosphorylation in lymphoid-specific helicase drives cancer stem-like pro...
近日,中南大学基础医学院、肿瘤研究所研究员陶永光团队在Signal Transduction and Targeted Therapy(IF=13.493)发表了题为“The Deubiquitylase UCHL3 Maintains Cancer Stem-Like Properties by Stabilizing the Aryl Hydrocarbon Receptor”的研究论文。中南...
近日,中南大学基础医学院、肿瘤研究所研究员陶永光团队在Signal Transduction and Targeted Therapy(IF=13.493)发表了题为“The Deubiquitylase UCHL3 Maintains Cancer Stem-Like Properties by Stabilizing the Aryl Hydrocarbon Receptor”的研究论文。中南...
近日,由四川大学华西医院/生物治疗国家重点实验室与Springer-Nature出版集团合办的英文学术期刊Signal Transduction and Targeted Therapy (STTT)被SCI数据库正式收录,首个影响因子预计将在今年6月获得。Signal Transduction and Targeted Therapy是四川大学华西医院生物治疗国家重点实验室和Springer-N...
Headlines, of late, have touted the successes of targeted gene-based cancer therapies, such as immunotherapies, but, unfortunately, also their failures.Broad inadequacies in a widespread biological co...
We are pleased to announce the Cold Spring Harbor Asia conference on Precision Cancer Biology: From Targeted to Immune Therapies which will be held in Suzhou, China, located approximately 60 miles wes...
The DNA Base Excision Repair (BER) pathway repairs DNA damaged by endogenous and exogenous agents including chemotherapeutic agents. Removal of the damaged base by a DNA glycosylase creates an apurini...
A revolution is underway in cancer therapy and care. Now, based on identifying in a patient’s cancer those genetic alterations that drive cancer growth, use of cancer therapy is more targeted and ca...
Oesophagogastric cancers are the fourth highest cause of cancer related deaths worldwide and the sixth most common cause of cancer related deaths in the Australian population. Their incidence has been...
Epithelial ovarian cancer is a challenging disease to treat, with the majority of patients presenting with advanced disease. Despite aggressive surgical debulking and platinum-based chemotherapy, many...
By delivering major improvements in patient outcomes, targeted therapies have revolutionised treatment paradigms for many haematological malignancies, particularly chronic myeloid leukaemia, acute pro...

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