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近日,国家卫健委肿瘤蛋白质组学重点实验室在国际权威杂志Signal Transduction and Targeted Therapy(信号转导与靶向治疗,IF=38.104)发表了题为“Targeting p53 pathways: mechanisms, structures, and advances in therapy”(靶向p53通路:机制、结构和治疗的进展)的文章。第一作者为博士研究...
肿瘤微环境(tumor microenvironment,TME)在肿瘤恶性和治疗抵抗中发挥着重要作用。近年来,根据TME特点挖掘潜在靶点并开发安全有效的免疫疗法逐渐成为乳腺癌治疗的研究热点。2018年7月27日,复旦大学生物医学研究院/附属肿瘤医院柳素玲团队在PLOS Biology杂志在线发表了题为CCL20 triggered by chemotherapy hinders the ther...
近日,中南大学基础医学院 肿瘤研究所研究员陶永光团队与病理学系教授肖德胜团队在国际期刊Signal Transduction and Targeted Therapy(STTT, IF=38.104)发表了题为“GPR162 activates STING dependent DNA damage pathway as a novel tumor suppressor and radiation ...
近日,中南大学湘雅医院病理科陶永光研究员与肖德胜教授团队在国际期刊Signal Transduction and Targeted Therapy(信号转导与靶向治疗,STTT,IF=38.104)发表了题为“GPR162 activates STING dependent DNA damage pathway as a novel tumor suppressor and radiation s...
肺结核病(TB,Tuberculosis)是由结核分枝杆菌(Mtb,Mycobacterium tuberculosis) 引起的肺部传染病,WHO 最新数据统计,仅 2019 年全球范围内有 1000 多万新病例并且有120 万死亡[1]。我国是肺结核病高负担国家,控制肺结核病的关键是有效药物治疗和早期诊断。然而,目前尚缺乏快速、安全的肺结核病临床诊断方法及抗肺结核病药物疗效评价生物标志物,也缺...
2021年12月26日, signal transduction and targeted therapy(影响因子13.493)在线刊发了基础医学院病理生理学系刘恭平教授团队研究成果:STAT3 ameliorates cognitive deficits by positively regulating the expression of NMDARs in a mouse model of ...
近日,中南大学基础医学院病理学系教授肖德胜团队与肿瘤研究所研究员陶永光团队在国际期刊Signal Transduction and Targeted Therapy发表了题为“The cross-talk between methylation and phosphorylation in lymphoid-specific helicase drives cancer stem-like pro...
近日,中南大学基础医学院、肿瘤研究所研究员陶永光团队在Signal Transduction and Targeted Therapy(IF=13.493)发表了题为“The Deubiquitylase UCHL3 Maintains Cancer Stem-Like Properties by Stabilizing the Aryl Hydrocarbon Receptor”的研究论文。中南...
近日,中南大学基础医学院、肿瘤研究所研究员陶永光团队在Signal Transduction and Targeted Therapy(IF=13.493)发表了题为“The Deubiquitylase UCHL3 Maintains Cancer Stem-Like Properties by Stabilizing the Aryl Hydrocarbon Receptor”的研究论文。中南...
近日,由四川大学华西医院/生物治疗国家重点实验室与Springer-Nature出版集团合办的英文学术期刊Signal Transduction and Targeted Therapy (STTT)被SCI数据库正式收录,首个影响因子预计将在今年6月获得。Signal Transduction and Targeted Therapy是四川大学华西医院生物治疗国家重点实验室和Springer-N...
Anti-aging proteins have long been shown to protect against age-related diseases, such as cancer, neurodegeneration, and cardiovascular disease. A study by researchers at the Gladstone Institutes now ...
Headlines, of late, have touted the successes of targeted gene-based cancer therapies, such as immunotherapies, but, unfortunately, also their failures.Broad inadequacies in a widespread biological co...
Essential tremor is the world’s most common movement disorder, affecting an estimated 7 million people in the U.S. alone. The hallmark of this disease is an involuntary, rhythmic shaking during intent...
Contact tracing -- a process of identifying everyone who has come into contact with those infected by a particular disease -- combined with targeted, indoor spraying of insecticide can greatly reduce ...
We are pleased to announce the Cold Spring Harbor Asia conference on Precision Cancer Biology: From Targeted to Immune Therapies which will be held in Suzhou, China, located approximately 60 miles wes...

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