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Genetic and Epigenetic Changes in Human Prostate Cancer
Genetics Epigenetics Genome Somatic Germline Prostate Cancer
2015/9/22
Acquired or inherited genetic alterations either alone or in combination with epigenetic alterations are associated with prostate carcinogenesis and its progression toward advance metastatic or castra...
Immunohistochemical study on the initiation of acid phosphatase secretion in the human prostate. Cytochemistry and biochemistry of acid phosphatases IV
Immunohistochemical study initiation acid phosphatase secretion human prostate
2009/2/19
Acid phosphatase was purified from human prostatic tissue and from seminal plasma. Antisera to antigens from both sources were raised in rabbits. These antisera have been used for immunohistochemical ...
Effects of liver disease and transplantation on the human prostate
Chronic liver disease prostate ultrasound androgen
2009/2/18
A major determinant of late-life prostate diseases is hormonal exposure during earlier life, but the effects of androgens in midlife on the human prostate have been little studied. In order to ide...
Expression and androgenic regulation of human prostate-specific kallikreins
Expression androgenic regulation human prostate-specific kallikreins
2009/2/13
In vitro studies suggest that the protease activity of PSA might play a functional role to facilitate the growth and spreading of cancerous prostatic cells. hK2 may have similar properties. Further ...
Androgen receptor regulation of G1 cyclin and cyclin-dependent kinase function in the CWR22 human prostate cancer xenograft
Androgen receptor regulation G1 cyclin cyclin-dependent kinase CWR22 huma prostate cancer
2008/12/29
Human prostate cancer is initially dependent on androgens for growth, and androgen-dependent cells undergo apoptosis after castration. However, a subset of androgen-responsive cells survives and event...
Differential expression of CCAAT/enhancer-binding protein-delta（c/EBPdelta）in rat androgen-dependent tissues and human prostate cancer
CCAAT/enhancer-binding protein-delta（c/EBPdelta） rat androgen-dependent tissues human prostate cancer
2008/12/26
CCAAT/enhancer-binding protein delta (C/EBPdelta) is a nuclear transcription factor that regulates cellular growth and differentiation. In this study we demonstrate that C/EBPdelta gene expression i...
Epidermal growth factor modulates the expression of vascular endothelial growth factor in the human prostate
Epidermal growth factor vascular endothelial growth factor human prostate
2008/12/26
The growth and dissemination of tumors in the body has been associated with angiogenesis. Vascular endothelial growth factor (VEGF) is an angiogenic factor that stimulates endothelial cell growth and ...
Drug-Metabolizing Enzymes and Transporters：Expression in the Human Prostate and Roles in Prostate Drug Disposition
Drug-Metabolizing Enzymes Transporters Human Prostate Prostate Drug Disposition
2008/12/23
Local biotransformation enzymes and transporter proteins in tissues may exert a profound effect on drug pharmacokinetics in those tissues. Thus, the use of drugs for the treatment of benign prostatic ...
Limited Processing of Pro-Matrix Metalloprotease-2（Gelatinase A）Overexpressed by Transfection in PC-3 Human Prostate Tumor Cells: Association With Restricted Cell Surface Localization of Membrane-Type Matrix Metalloproteinase-1
Tissue inhibitor of metalloproteinase-2 prostate cancer Concanavalin A reverse transcriptase-polymerase chain reaction
2008/12/22
The expression and activation of matrix metalloproteinases (MMPs) by tumor cells is correlated with progression to invasive and metastatic status. The purpose of this study was to examine the role of ...
Immunohistochemical Detection of the Retinoid X Receptors , ß, and in Human Prostate
Immunohistochemistry RxRs prostate cancer
2008/12/18
The aim of this study was to evaluate the presence and distribution of retinoid X receptors (RXRs) , ß, and in normal, hyperplastic (nodular, basal cell, and atrophic hyperplasia), and carc...
Immunohistochemical Localization of the Retinoic Acid Receptors in Human Prostate
Immunohistochemical Localization Retinoic Acid Receptors Human Prostate
2008/12/15
Retinoic acid receptors (RARs) are nuclear transcription factors that mediate the effects of retinoids. Aberrant expression and regulation of RARs have been linked to various malignancies, including s...