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The Association between Human Leukocyte Antigen Class II DR3–DQ2 Haplotype and Type 1 Diabetes in Children of the East Azerbaijan State of Iran
Haplotype Genotype HLA-DRB1 HLA-DQB1
2015/11/9
Background: Type 1 diabetes mellitus (T1D) is an autoimmune disease. Several associations between human leukocyte antigen (HLA) complex and T1D were found in various populations. Associations with var...
Haplotype based association study between t-PA gene and essential hypertension
Haplotype based association study t-PA gene essential hypertension
2009/4/20
Several previous studies have shown that essential hypertension (EH) is associated with fibrinolysis. Tissue plasminogen activator (t-PA) plays a key role in fibrinolysis. Thus, it is possible that ...
Association between Interleukin-10 Gene Promoter Haplotype and Schizophrenia in a Han-Chinese Study
schizophrenia IL-10 promoter region haplotypic analysis community
2009/4/14
Schizophrenia is a multi-factorial genetic disease, and it is caused by a combination of different gene polymorphisms and not individual ones, however, its pathogenesis is still unclear. The purpose o...
The nonprogressive motility of sperm populations from mice with a tw32 haplotype
nonprogressive motility sperm populations mice tw32 haplotype
2009/2/19
We have previously reported that epididymal spermatozoa from mice carrying a tw32 haplotype have a lower net velocity than do spermatozoa from congenic +/+ males. Using a test for nonprogressive mot...
Follicle-Stimulating Hormone Receptor Gene Haplotype Distribution in Normozoospermic and Azoospermic Men
Male infertility polymorphism SNP testis azoospermia
2008/12/23
The human follicle-stimulating hormone (FSH) receptor (FSHR) gene possesses single nucleotide polymorphisms (SNP) in exon 10, which influence serum FSH levels in women, but not in men. In the presen...
HLA Class II Allele and Haplotype Frequencies in Iranian Patients with Acute Myelogenous Leukemia and Control Group
Acute Myelogenous Leukemia HLA class II Polymorphism
2010/2/8
Previous studies have demonstrated some significant differences in HLA allele frequencies in leukemic patients and normal subjects. We have analyzed HLA class II alleles and haplotypes in 60 Iranian p...
Molecular-Based Haplotype Analysis of the β2-Adrenergic Receptor Gene (ADRB2) in Japanese Asthmatic and Non-Asthmatic Subjects
asthma haplotype Japanese population SNPs 2-adrenergic receptor
2010/11/18
Fifteen SNPs including a novel one in -839 were observed. Allele frequencies for all SNPs were similar between asthmatics and controls. We also identified 42 haplotypes and 54 diplotypes of ADRB2 in a...