搜索结果: 1-14 共查到“生物工程 disease”相关记录14条 . 查询时间(0.25 秒)
New technologies reveal cross-cutting breakdowns in Alzheimer’s disease（图）
阿尔茨海默病 交叉细分 单细胞分析 脑细胞
2023/6/21
After decades of fundamental scientific and drug discovery research, Alzheimer’s disease has remained inscrutable and incurable, with a bare minimum of therapeutic progress. But in a new review articl...
New gene-editing technique shows promise against sickle cell disease（图）
镰状细胞性贫血 基因编辑技术 一次性治疗
2023/6/21
Ateam of researchers led by scientists from Harvard and the Broad Institute used a new gene-editing technique to successfully treat sickle cell disease in mice. This advancement could one day lead to ...
Gene editing, or purposefully changing a gene’s DNA sequence, is a powerful tool for studying how mutations cause disease, and for making changes in an individual’s DNA for therapeutic purposes. A nov...
千淘万漉虽辛苦，吹尽狂沙始到金—记本科学员鲁洪廷、封仁乾与唐佳坤在《Cell Death & Disease》发表论文
Cell Death & Disease；较大影响力；刊物
2021/11/12
近日，空军军医大学基础医学院临床医学系2016级本科学员鲁洪廷、封仁乾，2017级学员唐佳坤在生理与病理生理学教研室周京军教授的指导下，所完成论文“CaMKII/calpain interaction mediates ischemia/reperfusion injury in isolated rat hearts”被《cell death & disease》刊用，该期刊属于Nature出版...
Why might the finding of a new genetic association with inflammatory bowel disease be of potential value in disease control?
new genetic association inflammatory bowel disease potential value disease control
2018/11/20
Inflammatory bowel disease (IBD) has long been recognized as an exaggerated inflammatory response to common antigenic stimuli in the gut. Ulcerative colitis (UC) (1) and Crohn disease (CD) (2) are the...
第八届DNA损伤应答与人类疾病国际研讨会（isDDRHD-2017）（8th international symposium on DNA Damage Response&Human Disease）
第八届 DNA损伤应答与人类疾病 国际研讨会
2017/8/31
第八届DNA损伤应答与人类疾病国际研讨会（international symposium on DNA Damage Response & Human Disease, isDDRHD-2017）将于2017年10月27-29日在深圳大学召开。DNA损伤应答与人类疾病国际研讨会（isDDRHD）是由许兴智教授和Zhao-Qi Wang院士于2010年共同发起，旨在为DNA修复领域的中国学者与国际主...
Researchers have developed a method to swiftly screen the non-coding DNA of the human genome for links to diseases that are driven by changes in gene regulation. The technique could revolutionize mode...
2017细胞命运和疾病基因组结构戈登学术会议（The 2017 Gordon Research Conference on Genome Architecture in Cell Fate&Disease ）
2017 细胞命运和疾病基因组结构戈登 学术会议
2017/2/14
Accumulating evidence suggest that genomes are organized non-randomly into complex 3D configurations that vary according to cell type, stage of development, differentiation and disease status. The pri...
Gene editing study reveals possible 'Achilles heel' of sickle cell disease
Gene editing study Achilles heel sickle cell disease
2015/9/25
Researchers from Dana-Farber/Boston Children's Cancer and Blood Disorders Center have found that changes to a small stretch of DNA may circumvent the genetic defect behind sickle cell d...
Human Niemann-Pick Type C2 Disease Protein Expression, Purification and Crystallization
Niemann-Pick type C2 NPC2 Structure Expression Crystallization Purification
2014/12/12
Niemann-Pick type C2 (NPC2) protein is a soluble protein that binds unesterified cholesterol. The protein helps transport unesterified cholesterol in tandem with the membrane protein Niemann-Pick type...
Pathways to dementia: genetic predictors of cognitive and brain imaging endophenotypes in Alzheimer's disease
Episodic memory Amyloid plaque
2015/5/21
Alzheimer's disease (AD) is a national priority, with nearly six million Americans affected at an annual cost of $200 billion and no available cure. A better understanding of the mechanisms underlying...
ROLE OF GENOMIC COPY NUMBER VARIATION IN ALZHEIMER'S DISEASE AND MILD COGNITIVE IMPAIRMENT
Copy number variation Alzheimer's disease
2015/5/21
Alzheimer's disease (AD) is the most common form of dementia defined by loss in memory and cognitive abilities severe enough to interfere significantly with daily life activities. Amnestic mild cognit...
阿尔茨海默病中β淀粉样前体蛋白基因外显子9、10的mRNA表达及突变研究--Expression Variation and Mutation Analysis of Exon 9 and 10 in Amyloid Precursor Protein Gene in Alzheimer′s Disease
阿尔茨海默病 β淀粉样前体蛋白基因 表达 突变
2007/12/5
于上海地区汉人群中，探讨阿尔茨海默病(AD)患者外周血中β淀粉样前体蛋白基因外显子9、10（APP9~10）的mRNA表达水平，并作cDNA的点突变检测。采用半定量竞争性反转录聚合酶链反应(semi-quantitive competitive RT-PCR)技术测定APP9~10的mRNA表达水平；以聚合酶链反应（PCR）-限制性片段长度多态(RFLP)方法检测基因组DNA中载脂蛋白E基因(AP...
KU researchers explore human disease through tiny roundworm（图）
human disease roundworm muscular dystrophy
2006/12/8
Dec. 1, 2006，LAWRENCE — University of Kansas researchers are learning a lot about humans from a tiny roundworm.Researchers commonly use the worm, Caenorhabditis elegans, or C. elegans, to study a rang...