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南京农业大学农学院《Nucleic Acids Research》发表张文利教授团队“The roles of DNA methylation on pH dependent i-motifs (iMs) formation in rice”（图）
张文利 基因 解析
2024/6/11
2024年1月8日，农学院张文利课题组在 “Nucleic Acids Research”上发表了题为“The roles of DNA methylation on pH dependent i-motifs (iMs) formation in rice”的研究论文。该研究是在前期的研究基础之上（Nucleic Acids Res 2022, 50:3226-3238），再次利用iM-IP-s...
Impact of polyunsaturated and saturated fat overfeeding on the DNA-methylation pattern in human adipose tissue: a randomized controlled trial
DNA methylation epigenetics EWAS Illumina 450k methylation array LIPOGAIN cohort obesity overfeeding polyunsaturated fat prediction saturated fat
2018/11/13
Background: Dietary fat composition can affect ectopic lipid accumulation and, thereby, insulin resistance. Diets that are high in saturated fatty acids (SFAs) or polyunsaturated fatty acids (PUFAs) h...
Repeats as global DNA methylation marker in bovine preimplantation embryos
epigenetics retrotransposon bisulfite sequencing
2017/2/21
DNA methylation undergoes dynamic changes and is a crucial part of the epigenetic regulation during mammalian early development. To determine the DNA methylation levels in bovine embryos, we applied a...
LIM homeodomain 3 (LHX3) is an important regulator of pituitary and nervous system development. To date, twelve LHX3 gene mutations have been identified in patients with combined pituitary hormone def...
Association of DNA Methylation Levels with Tissue-specific Expression of Adipogenic and Lipogenic Genes in Longissimus dorsi Muscle of Korean Cattle
Adipogenesis DNA Methylation Intramuscular Fat Korean Cattle
2016/5/17
Epigenetic factors, such as DNA methylation status, may regulate adipogenesis and lipogenesis, thus affecting intramuscular fat (IMF) deposition in longissimus dorsi muscle (LM) of beef cattle. In Kor...
DNA甲基化与组蛋白甲基化的关系The Relationship of DNA Methylation and Histone Methylation
DNA 组蛋白 甲基化 甲基转移酶
2008/1/10
摘要在真核生物基因组及基因组以外，存在着多种共价修饰，其中，DNA和组蛋白的甲基化都与基因的沉默存在着联系，DNA和H3K9的甲基化在调节基因过程中具有协同作用，并拮抗H3K4的甲基化。近来的研究显示，两种甲基化机制之间似乎还存在着联系，即DNA的甲基化可能依赖于H3K9的甲基化，但在哺乳动物中，两种甲基化的关系可能更复杂。 Abstract: In and out of the eukaryot...
Genome-wide DNA Methylation Profiles of Small Intestine and Liver in Fast-growing and Slow-growing Weaning Piglets
DNA Methylation MBD-seq Epigenetic Profile Weaning Piglet Genome-wide Methylation Profile
2016/5/17
Although growth rate is one of the main economic traits of concern in pig production, there is limited knowledge on its epigenetic regulation, such as DNA methylation. In this study, we conducted meth...